Treating tenosynovial giant cell tumor (TGCT) takes a team

Your team to treat TGCT

Having a multidisciplinary care team means there are different healthcare professionals working together to give you the best treatment and care; keeping them informed about how you’re feeling will help them help you.


TGCT is not cancerous, but sometimes oncologists who specialize in cancer can help treat your TGCT. Oncologists understand how tumors grow and may be able to help you make treatment decisions—which is why they are the typical treaters of TGCT.

Hand surgeons

Localized TGCT usually occurs in the hand. Patients with small, localized tumors in the hand may be referred to hand surgeons for their expert knowledge and skill set.

Pain management specialists

Physicians, nurses, psychologists, and rehabilitation specialists can treat pain. Talk with your healthcare team to find a pain specialist.

Orthopedic surgeons

Orthopedic surgeons diagnose and treat disorders of the bones, joints, ligaments, tendons, and muscles. Patients diagnosed with TGCT or those who have symptoms of TGCT may be referred to orthopedic surgeons for their expert knowledge. General orthopedic surgeons may not be familiar with the disease, but orthopedic oncologists are skilled in treating TGCT.

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Advanced practitioners

Nurse practitioners and physician assistants who specialize in oncology or orthopedics may have the expertise to manage treatment and long-term care for patients with TGCT that is recurrent, diffuse, or difficult to treat. These advanced practitioners may perform exams, order and evaluate laboratory tests, and provide pre- and post-treatment patient education.


Pathologists analyze samples of tissues or bodily fluids. They confirm the presence of certain substances, and this work helps doctors diagnose and manage TGCT.

Physical therapists and rehabilitation specialists

These specialists may play a role in diagnosing TGCT. They may also help patients with post-surgery recovery.


Radiologists perform tests and assess the results. The tests may include X-rays, magnetic resonance imaging (MRI), and ultrasound.

A discussion guide to help lead
your treatment conversation

Discover helpful questions to ask at your next doctor visit.

There are other TGCT treatment options aside from surgery

Surgery is often the first course of action, but if you and your care team decide surgery is not likely to improve your condition, there are other treatment options available for you.

Depending on severity, TGCT can return after surgery in 4 years or sooner. The estimated recurrence rate for diffuse TGCT is up to 55%. Multiple surgeries can be painful and limit your range of motion, with risk of infection.

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Estimated recurrence rate for diffuse TGCT

I became my own best advocate.


Siobhan, Turalio patient and brand ambassador since 2021
Siobhan, Turalio patient and brand ambassador since 2021

For patients with TGCT not likely to improve with surgery, talk to a doctor about Turalio® (pexidartinib) as a treatment option.

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